British Association of Dermatologists
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Introduction
Glossary
What is pemphigus vulgaris?
What types of pemphigus are there?
What areas of the body are affected by pemphigus vulgaris?
What does pemphigus vulgaris look like?
Who tends to have pemphigus vulgaris?
What causes pemphigus vulgaris?
Is pemphigus vulgaris hereditary?
Is pemphigus vulgaris catching?
Is pemphigus vulgaris serious?
Are there any complications with pemphigus vulgaris?
Does anything make pemphigus vulgaris worse?
Does anything make pemphigus vulgaris worse?
How will pemphigus vulgaris be diagnosed?
How can pemphigus vulgaris be treated?
What does it mean if I am told my pemphigus vulgaris is in 'remission'?
Managing a pemphigus vulgaris 'flare-up'
What can I do to help myself?
How will pemphigus vulgaris affect my daily life?
I am about to see a health care professional; what do I ask him or her?
Other frequently asked questions (FAQ)
What do I do next?
Where can I get more information?
Print Page
>> Authors
Siri Lowe; Founder and Chief Executive for the Pemphigus Vulgaris Network
Mary Jane Watts, RGN, ENB393; Dermatology Nurse Practitioner; Whipps Cross University Hospital, London
Dr Karen Harman, MA, MRCP, DM. Consultant Dermatologist, University Hospitals, Leicester
Dr Joanne Chalmers BSc PhD; Research Associate, University of Nottingham
Professor Hywel C Williams MSc PhD FRCP, Professor of Dermato-Epidemiology, University of Nottingham

Date written: July 2005
Date to be updated: July 2007


References

  1. Burge SM. Hailey-Hailey disease. In: Burns T, Breathnach S, Cox N, Griffiths C, eds. Textbook of Dermatology. 7th edition. Oxford: Blackwell Science, 2004: 40.32-40.36.
  2. Burge SM. Hailey-Hailey disease. In: Burns T, Breathnach S, Cox N, Griffiths C, eds. Textbook of Dermatology. 7th edition. Oxford: Blackwell Science, 2004: 41.5-41.13.
  3. Harman KE, Gratian MJ, Bhogal BS, Challacombe SJ, Black MM. A study of desmoglein 1 autoantibodies in pemphigus vulgaris: racial differences in frequency and the association with a more severe phenotype. Br J Dermatol 2000;143:343-348.
  4. Becker BA, Gaspari AA. Pemphigus vulgaris and vegetans. Dermatol Clin 1993;11(3):429-52.
  5. Anhalt GJ, Labib RS, Voorhees JJ, Beals TF, Diaz LA. Induction of pemphigus in neonatal mice by passive transfer of IgG from patients with the disease. N Engl J Med 1982;306(20):1189-96.
  6. Amagai M, Hashimoto T, Shimizu N, Nishikawa T. Absorption of pathogenic autoantibodies by the extracellular domain of pemphigus vulgaris antigen (Dsg3) produced by baculovirus. J Clin Invest 1994;94(1):59- 67.
  7. Bystryn JC, Steinman NM. The adjuvant therapy of pemphigus. An update. Arch Dermatol 1996;132(2):203-12.
  8. Ratnam KV, Phay KL, Tan CK. Pemphigus therapy with oral prednisolone regimens. Int J Dermatol 1990;29:363-7.
  9. Carson PJ, Hameed A, Ahmed AR. Influence of treatment on the clinical course of pemphigus vulgaris. J Am Acad Dermatol 1996;34(4):645-52.
  10. Tur E, Brenner S. Contributing exogenous factors in pemphigus. Int J Dermatol 1997;36:999-93.
  11. Brenner S, Wolf R. Possible nutritional factors in induced pemphigus. Dermatology 1994;189:337-9.
  12. Mutasim DF, Pelc NJ, Anhalt GJ. Drug-induced pemphigus. Dermatologic Clinics 1993;11(3):463-71.
  13. Herbst A, Bystryn J-C. Patterns of remission in pemphigus vulgaris. J Am Acad Dermatol 2000;42:422-7.
  14. Kyriakis KP, Tosca AD. Epidemiologic observations on the natural course of pemphigus vulgaris. Int J Dermatol 1998;37:215-219.
  15. Harman KE, Gratian MJ, Seed PT, Bhogal BS, Challacombe SJ, Black MM. Diagnosis of pemphigus by ELISA: a critical evaluation of two ELISAs for the detection of antibodies to the major pemphigus antigens, desmoglein 1 and 3. Clin Exp Dermatol 1999;25:236-240.
  16. Harman KE, Albert S, Black MM. Guidelines for the management of pemphigus vulgaris. Br J Dermatol 2003;149:926-37.
  17. Society BaT, Society NO, Physicians RCo. Glucocorticoid-induced osteoporosis: guidelines for prevention and treatment. London: RCP, 2002.

Anecdotal evidence from the pemphigus vulgaris network has been incorporated into this website.


Acknowledgments

We are grateful for the input of the International Pemphigus Foundation via their website: http://www.pemphigus.org

 

 

 

 

 

 

 

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