Nobody knows exactly. This is because there have not been any really good
studies to accurately measure the number of people affected by latex allergy.
The best estimate at the moment is that it probably affects less than 1% of
the general population (1).
It also seems to be rare in children (2).
Latex allergy is more common in certain groups of people such as those with:
Atopy
Atopy is a tendency whereby some become sensitized and produce IgE
antibodies in response to ordinary exposure to allergens (3) (see 'What is
latex allergy?'). Atopy is common among people with latex allergy, and is an important
risk factor. Eczema, asthma and hay fever are common “atopic” diseases.
Spina bifida and operations / catheterisations
Children with spina bifida have the highest incidence of latex allergy. This is
because of repeated exposure of the mucous membranes to NRL from
operations and catheterizations (LINK). People who have undergone
operations for other reasons may also be at increased risk. (4, 5)
High workplace exposure
People who are regularly exposed to NRL in the course of their occupation
are at increased risk of developing latex allergy (12)
For example, studies in healthcare workers show a sensitisation rate (positive
latex allergy tests) of about 10%, although allergic reactions are much less
common (see 'What is latex allergy?') (6, 7)
Many healthcare workers became allergic to latex in the 1990’s when highprotein,
powdered latex gloves were in routine use (see 'History of latex allergy').
Because of this, a change was made to using low-protein, non-powdered
gloves, which has significantly reduced the number developing latex allergy
(8,9).
Hand dermatitis
Pre-existing hand dermatitis (10) is a risk factor for latex allergy.
People with hand dermatitis often wear latex gloves in an attempt to protect
their skin from chemicals or other hazardous materials, but because their skin
is already damaged from the dermatitis, latex proteins easily penetrate the
skin and sensitisation then becomes more likely.
For the same reason, people with hand dermatitis are also at increased risk of
developing rubber chemical allergy. (see 'What is latex allergy?')
Hand dermatitis is more common in atopic individuals, whose skin is easily
irritated by soaps, detergents, oils and solvents.
Allergy to fruits
People who are allergic to fruits may also become allergic to latex (see the 'food page')(11)
Bibliography
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