British Association of Dermatologists
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Introduction
Glossary
What is latex allergy?
History of latex allergy
What things contain latex?
How common is latex allergy?
What will happen to me if I have an allergic reaction?
How is latex allergy diagnosed?
Is latex allergy serious?
Does latex allergy go away?
What can I do to help prevent an allergic reaction to latex?
How are allergic reactions to latex treated?
How do hospitals deal with latex allergy?
What gloves are used in healthcare?
What should I do when I visit the dentist?
How will latex allergy affect my daily life?
Can people with latex allergy also have food allergy?
What gloves can I wear if I am allergic to latex?
Why is glove powder a problem?
Frequently Asked Questions
Where can I get further information?
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>> How common is latex allergy?

Nobody knows exactly. This is because there have not been any really good studies to accurately measure the number of people affected by latex allergy.

The best estimate at the moment is that it probably affects less than 1% of the general population (1).

It also seems to be rare in children (2).

Latex allergy is more common in certain groups of people such as those with:

Atopy

Atopy is a tendency whereby some become sensitized and produce IgE antibodies in response to ordinary exposure to allergens (3) (see 'What is latex allergy?'). Atopy is common among people with latex allergy, and is an important risk factor. Eczema, asthma and hay fever are common “atopic” diseases.

Spina bifida and operations / catheterisations

Children with spina bifida have the highest incidence of latex allergy. This is because of repeated exposure of the mucous membranes to NRL from operations and catheterizations (LINK). People who have undergone operations for other reasons may also be at increased risk. (4, 5)

High workplace exposure

People who are regularly exposed to NRL in the course of their occupation are at increased risk of developing latex allergy (12)

For example, studies in healthcare workers show a sensitisation rate (positive latex allergy tests) of about 10%, although allergic reactions are much less common (see 'What is latex allergy?') (6, 7)

Many healthcare workers became allergic to latex in the 1990’s when highprotein, powdered latex gloves were in routine use (see 'History of latex allergy'). Because of this, a change was made to using low-protein, non-powdered gloves, which has significantly reduced the number developing latex allergy (8,9).

Hand dermatitis

Pre-existing hand dermatitis (10) is a risk factor for latex allergy. People with hand dermatitis often wear latex gloves in an attempt to protect their skin from chemicals or other hazardous materials, but because their skin is already damaged from the dermatitis, latex proteins easily penetrate the skin and sensitisation then becomes more likely.

For the same reason, people with hand dermatitis are also at increased risk of developing rubber chemical allergy. (see 'What is latex allergy?')

Hand dermatitis is more common in atopic individuals, whose skin is easily irritated by soaps, detergents, oils and solvents.

Allergy to fruits

People who are allergic to fruits may also become allergic to latex (see the 'food page')(11)


Bibliography

(1) Latex allergy: prevalence, risk factors, and cross-reactivity
(2) Prevalence of latex allergy in the community at age 7 years
(3) http://en.wikipedia.org/wiki/Atopy
(4) Impact of repeated surgical procedures on the incidence and prevalence of latex allergy: a prospective study of 1263 children
(5) http://www.blackwell-synergy.com/links/doi/10.1034/j.1398-9995.2001.00021.x/pdf
(6) Natural rubber latex allergy in a health-care population in Wales
(7) http://occmed.oupjournals.org/cgi/reprint/51/8/510.pdf
(8) Decreasing incidence of occupational contact urticaria caused by natural rubber latex allergy in German health care workers
(9) Contact dermatoses in healthcare workers: reduction in type I latex allergy in a UK centre
(10) http://dermnetnz.org/dermatitis/hand-dermatitis.html
(11) Latex allergy in fruit-allergic patients
(12) Allergic contact urticaria from natural rubber latex in healthcare and non-healthcare workers

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