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Bowen's Disease

 

What are the aims of this leaflet?

This leaflet has been written to help you understand more about Bowen’s disease.  It tells you what it is, what causes it, what can be done about it, and where you can find out more about it.

 

What is Bowen’s disease?

Bowen’s disease is a skin growth, which is confined to the outer layer of the skin.  It usually appears as a slow-growing red and scaly patch. Occasionally one can turn into true skin cancer.  For this reason, dermatologists usually treat or at least keep an eye on Bowen's disease.  

 

What causes Bowen’s disease?

It is thought to develop partly as a result of long-term sun exposure.  It is seen most often on the legs of women. Bowen's disease is not infectious or due to an allergy.  

 

Is it hereditary?

No, it is not; but some of the things that increase the risk of getting one, such as a fair skin and a tendency to burn in the sun, do run in families.

 

What are its symptoms?

Often there are no symptoms although the surface crusting may catch on clothing.  

 

What does it look like?

A patch of Bowen’s disease starts as a small red scaly area, which grows very slowly.  It may reach a diameter of a few centimetres across.  The commonest site is the lower leg, mainly in women.  About a fifth of women with it have more than one patch.  After many years, a small minority of patches - perhaps about 1 in 50 - turn into a type of skin cancer (a squamous cell carcinoma).  An ulcer, or a small bump, coming up on the original patch of Bowen’s disease, can signal this change. 

  

How will it be diagnosed?

A patch of Bowen’s disease can look rather like other skin conditions, such as psoriasis.  For this reason a biopsy may be needed to make the diagnosis.

 

Can it be cured?

Yes, there are a variety of ways in which this can be achieved (see below). 

 

How can it be treated?

Several treatments are available for Bowen’s disease, such as freezing it, scraping it off the skin (curettage), and surgical removal.  In some cases a cream known as 5-fluorouracil (Efudix cream) may be used.  Photodynamic therapy is available in some clinics now: radiotherapy (X-ray treatment) is being used less often.  

 

However a particular problem is that Bowen’s disease is usually found on the lower leg - where the skin is often tight and sometimes quite fragile, especially in older patients.  Healing there is slow.  Many factors, therefore, play a part in selecting the right treatment:

·       The size and thickness of the patch.

·       The number of patches.

·       The presence of swelling of the legs.

·       The general state of the skin on the legs.

 

If your patch is judged to be thin and not troublesome, your dermatologist may simply suggest that it is kept under observation in a clinic, or in some cases by yourself or by your GP.

 

Treatment details:

·       Freezing – this is done in the clinic.  It causes redness, puffiness, blistering or crusting, and may be slow to heal.  It can be done in stages for large areas of Bowen's disease.

·       Curettage – this is scraping off the abnormal skin under a local anaesthetic.  The area then heals with a scab, like a graze.

·       Excision (cutting the patch out) – is done under local anaesthetic.  Usually it involves stitching the skin to close the area.

·       Efudix cream – this is a cream that may control or eradicate the disorder.  There are various different ways of using it, and, if it is felt to be the best treatment, the doctor who sees you will explain these to you.  Efudix works by killing the abnormal skin cells.  This means that the skin will become red and look worse during treatment, and will then heal after the end of the course of treatment, once the abnormal cells have gone.  Often a daily non-adhesive dressing is needed during the treatment.  

·       Photodynamic therapy – is a new form of treatment.  A chemical is applied to the skin that makes the cells in the patch of Bowen’s disease sensitive to particular wavelengths of light.  The treatment is associated with some pain and inflammation.  Dressings may be needed before healing takes place.

 

What can I do?

·       From now on, you should take sensible precautions to stop another patch of Bowen’s disease coming up.  This means wearing clothing that protects you against the sun, avoiding strong sunlight, and using a sun block of at least Factor 30.

·       The smaller your patch of Bowen’s disease is, the better the results of treatment are likely to be.  If you think another one is coming up, see your doctor about it early rather than late

·       If your patch changes in any way (bleeds, or develops an ulcer, or a bump, on top) contact your doctor quickly as this could be the start of an invasive skin cancer.

 

Where can I get more information?

 

Reference used in the text:  ‘Guidelines for the management of Bowen’s Disease.’  British Journal of Dermatology, Vol. 141, Number 4, October 1999, pages 633 to 641.

 

Web link to detailed leaflet:  www.emedicine.com/derm/topic59.htm

 

(While every effort has been made to ensure that the information given in this leaflet is accurate, not every treatment will be suitable or effective for every person. Your own doctor will be able to advise in greater detail)

 

BAD PATIENT INFORMATION LEAFLET

PRODUCED AUGUST 2004

 

 

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