Patient Information Leaflets (PILs)

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These Patient Information Leaflets (PILs) are specially written by the British Association of Dermatologists (BAD).

The BAD has been awarded The Information Standard certification for the process it employs to develop information products aimed at the general public, which include PILs, Sun Awareness Campaign materials, and other information products.

The BAD shall hold responsibility for the accuracy of the information published, and neither the scheme operator nor the scheme owner shall have any responsibility for costs, losses, or direct or indirect damages or costs arising from inaccuracy of information or omissions in information published on the website on behalf of the BAD.

Displaying item Erythema multiforme

Erythema multiforme (EM) is a hypersensitivity reaction which tends to develop abruptly. Usually it will disappear on its own, but sometimes treatment may be required for the symptoms. It occurs in all racial groups and is predominantly observed in young adults (20-40 years), but can occur in any age group. The condition is slightly more common in men. 

Erythema multiforme is characterised by the sudden development of few to hundreds of red papules (spots). The papules usually begin over the back of the feet and hands, and spread upwards towards the trunk. The face is often involved. The hands and arms are more commonly affected than the feet and legs. Over time these papules evolve to plaques (raised patches) and then typical target shaped lesions. These target lesions have a dusky red centre, a paler area around this, and then a dark red ring round the edge. Sometimes the centre of the target can be crusted or blistered. The targets can be different shapes and sizes, hence the latin name: erythema (redness) multi (many), forme (shapes). 

Erythema multiforme is usually mild - 'erythema multiforme minor' – with only skin involvement, causing little trouble and clearing quickly.  There is also a rare but more severe type, 'erythema multiforme major', which has similar skin features to EM minor, but additionally there is involvement of one or more mucosal membrane (e.g. the lips, the inside of the mouth, the windpipe, the gullet, the anus or genital area, and the eyes) and usually some associated symptoms, such as fever or joint pain.

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