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Patient Information Leaflets (PILs)

These Patient Information Leaflets (PILs) are specially written by the British Association of Dermatologists (BAD).

The BAD has been awarded The Information Standard certification for the process it employs to develop information products aimed at the general public, which include PILs, Sun Awareness Campaign materials, and other information products.

The BAD shall hold responsibility for the accuracy of the information published, and neither the scheme operator nor the scheme owner shall have any responsibility for costs, losses, or direct or indirect damages or costs arising from inaccuracy of information or omissions in information published on the website on behalf of the BAD.

Please note:

  1. There are thousands of different skin complaints, therefore, the focus of the British Association of Dermatologists' PILs production is on the most common, rarest or debilitating skin conditions.
  2. The offer to provide details of source materials used to inform the British Association of Dermatologists' PILs is for instances where the advice provided in the PILs does not reflect local practice and therefore evidence supporting said advice needs to be produced. It is not an offer to conduct literature searches or supply bibilographic materials for your own research.
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Cutaneous amyloidosis

Amyloidosis or ‘amyloid’ is group of rare diseases in which abnormal proteins, accumulate in various organs including the skin. The name ‘amyloid’ was given to the condition over 150 years ago because the deposits looked like starch under the microscope. (In Latin amylum = starch).

In primary localised cutaneous amyloidosis (PLCA) amyloid deposits only occur in the skin. The exception to this is a rare disease called nodular amyloid, which can be associated with amyloid deposits in other body organs and myeloma (a form of bone marrow cancer).

PLCA is uncommon in Europeans and occurs more frequently in people who originate from South-East Asia, South America and the Middle East. It usually starts in adult life and tends to persist for many years. 

There are three main forms of PLCA: Macular amyloidosis, lichen / papular amyloidosis and Nodular amyloidosis (the rarest form).

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